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"Duc in altum" is a Latin phrase from the Vulgate translation of Luke 5:4: "put out into the deep" or "launch into the deep". Jesus speaks these words to Simon Peter, telling him to cast his nets into the deep for a catch, which results in a miraculous abundance of fish.
Pope St. John Paul II spoke on this subject of “putting out into the deep” several times, including at the 2005 World Day of Prayer for Vocations, he said, “One needs to open one’s heart to the abundance of grace and to allow the word of the Redeemer to act with all its power: ‘Duc in altum!’ Whoever opens his heart to Christ will not only understand the mystery of his own existence, but also that of his own vocation; he will bear the abundant fruit of grace.”